Cialis (Cialis)
Erectile Dysfunction Treatment
Cialis (Tadalafil) is a long-lasting erectile dysfunction treatment known as 'The Weekend Pill'. It can remain effective for up to 36 hours, offering greater spontaneity compared to other ED medications.
Table of Contents
Cialis Product Information
Cialis is a branded erectile dysfunction treatment containing the active ingredient tadalafil. Often referred to as 'The Weekend Pill', Cialis is known for its long-lasting effects, which can remain active for up to 36 hours after taking a single dose. This extended duration offers men greater flexibility and spontaneity in their sexual activity.
Cialis works in the same way as other PDE5 inhibitors but has a significantly longer duration of action. It was developed by Eli Lilly and has been available since 2003. Clinical studies have shown that Cialis is effective in approximately 81% of men with erectile dysfunction.
In addition to treating erectile dysfunction, tadalafil (the active ingredient in Cialis) is also approved for the treatment of benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension under different brand names.
Cialis works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that breaks down cGMP in the penis. During sexual stimulation, nitric oxide is released, which activates cGMP production. By blocking PDE5, Cialis allows cGMP to accumulate, relaxing the smooth muscles and increasing blood flow to the penis, resulting in an erection. The unique molecular structure of tadalafil gives it a longer half-life compared to sildenafil, which is why its effects last up to 36 hours.
Take one Cialis tablet at least 30 minutes before sexual activity. Swallow the tablet whole with water. Cialis can be taken with or without food. Do not take more than one tablet per day. For daily use, a lower dose (2.5mg or 5mg) may be prescribed by your doctor.
Cialis typically begins to work within 30 minutes of taking the tablet, with peak effectiveness reached at around 2 hours. Some men may notice effects as early as 15 minutes after taking the medication.
Cialis is effective for up to 36 hours after taking a single dose, earning it the nickname 'The Weekend Pill'. This does not mean you will have an erection for 36 hours — sexual stimulation is still required to achieve an erection during this window.
Cialis Quick View
| Active Ingredient | Tadalafil |
|---|---|
| Manufacturer | Eli Lilly |
| Type | PDE5 Inhibitor |
| Onset | 30 minutes |
| Duration | Up to 36 hours |
| Food Interaction | Can be taken with or without food |
| Alcohol | Limit alcohol consumption |
| Prescription | Prescription required |
Cialis Side Effects
Common Side Effects
- Headache
- Back pain
- Muscle aches
- Flushing
- Indigestion
- Nasal congestion
Uncommon Side Effects
- Dizziness
- Stomach pain
- Excessive sweating
- Blurred vision
Rare Side Effects
- Priapism (prolonged erection)
- Sudden hearing loss
- Sudden vision loss
- Chest pain
Important Warning: Seek immediate medical attention if you experience a painful erection lasting more than 4 hours, sudden loss of vision or hearing, or chest pain. Do not take Cialis with nitrates or alpha-blockers without medical supervision.
More Information About Cialis
Storage
Store below 30°C in the original packaging. Keep out of reach of children.
Contraindications
Do not take if allergic to tadalafil. Do not take with nitrates or nitric oxide donors. Not suitable for those with severe heart conditions, recent stroke or heart attack, or severe liver/kidney impairment.
Drug Interactions
May interact with nitrates, alpha-blockers, antifungal medications, HIV protease inhibitors, and certain antibiotics. Grapefruit juice may increase tadalafil levels in the blood.
Cialis FAQs
The main difference is duration. Cialis lasts up to 36 hours compared to Viagra's 4-6 hours. Cialis can also be taken with food without affecting its efficacy, while Viagra may be delayed by heavy meals.
Yes, Cialis is available in a daily dose (2.5mg or 5mg) for men who have sex more than twice a week. This allows for spontaneous sexual activity without planning around taking a pill.
Cialis has been extensively studied and is considered safe for most men with erectile dysfunction. However, it is not suitable for everyone. Always consult your doctor before starting treatment.
Moderate alcohol consumption is generally acceptable with Cialis. However, excessive alcohol can increase the risk of side effects and may impair your ability to achieve an erection.
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Content last updated: 27 Mar 2026
Cialis Reviews
Based on 15,420 reviews
Cialis is incredible. The 36-hour window gives so much flexibility. No need to plan everything around a pill.
Switched from Sildenafil to Cialis and never looked back. The longer duration is a massive advantage.
Very effective medication. Takes a bit longer to start working compared to Sildenafil but lasts much longer.
The daily low-dose option has been perfect for me. Spontaneity is back in my life.
Great results. Mild back pain the first couple of times but it went away. Very satisfied overall.
Best ED medication I've tried. Works reliably and the extended duration is a real game-changer.
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