Atarax (Atarax)

Antihistamine Treatment

Hydroxyzine is an antihistamine used to treat anxiety, tension, and itching caused by allergic reactions. It also acts as a sedative to promote relaxation before medical procedures.

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Atarax Product Information

Hydroxyzine is a first-generation antihistamine primarily used to manage anxiety and tension associated with nervous and emotional conditions. It is also effective in controlling anxiety and inducing sleep prior to surgical procedures. Additionally, hydroxyzine is prescribed to alleviate symptoms of allergic conditions, including chronic urticaria, atopic dermatitis, and contact dermatoses.

The medication works by blocking the action of histamine, a natural substance in the body responsible for allergic symptoms. It also exerts a sedative effect by decreasing activity in the brain.

Hydroxyzine is an antihistamine that works by blocking the effects of histamine, a substance produced by the body that causes allergic symptoms. It also acts as a central nervous system depressant, reducing activity in the brain to help control anxiety and promote relaxation.

Hydroxyzine is available as capsules, tablets, and a syrup (solution) and is taken by mouth. It is usually taken three or four times a day or as directed by your doctor. It is crucial to take hydroxyzine exactly as prescribed, without taking more or less, or more often than instructed by your doctor.

Hydroxyzine typically starts to show clinical effects within 15 to 30 minutes, with peak levels occurring approximately 2 hours after administration.

The noticeable calming and sedating effects of hydroxyzine typically last for about 4 to 6 hours.

Atarax Quick View

Active Ingredient Hydroxyzine
Manufacturer Common manufacturers include Pfizer (Vistaril), Teva Pharmaceuticals USA, Morton Grove Pharmaceuticals, Inc., LGM Pharma, Chemische Fabrik Berg, Jai Radhe Sales, and Malladi Drugs & Pharmaceuticals Limited.
Type First-generation antihistamine
Onset Clinical effects are typically observed within 15-30 minutes, with peak plasma levels reached at approximately 2 hours.
Duration The noticeable calming and sedating effects typically last about 4-6 hours.
Food Interaction No specific food interactions are commonly reported, but it is generally advised to avoid alcohol.
Alcohol Not recommended. Alcohol can increase nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. It can dangerously enhance sedation, dizziness, and impair motor skills.
Prescription Prescription only

Atarax Side Effects

Common Side Effects

  • Dry mouth
  • Confusion (especially in older adults)
  • Dizziness
  • Headache
  • Drowsiness
  • Fatigue

Uncommon Side Effects

  • Urinary retention
  • Blurred vision
  • Irritability

Rare Side Effects

  • Unintentional trembling or shaking movements
  • Seizures
  • Rash, pus-filled, blister-like sores, areas of swelling and redness on the skin, and fever
  • Chest pain, discomfort, or tightness
  • Cough
  • Difficulty with swallowing
  • Fainting
  • Fast heartbeat
  • Hives, itching, or skin rash
  • Irregular or slow heart rate
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Trouble breathing
  • Unusual tiredness or weakness

Important Warning: Seek immediate medical attention if you experience serious side effects such as unintentional trembling or shaking movements, seizures, severe skin reactions, or symptoms of an irregular heartbeat. Overdose symptoms may include severe sedation and seizures.

More Information About Atarax

Storage

Keep this medication in its original container, tightly closed, and out of reach of children. Store at room temperature, away from light, excessive heat, and moisture (do not store in the bathroom). Dispose of unneeded medications safely to prevent access by pets, children, or others, preferably through a medicine take-back program.

Contraindications

Known hypersensitivity to hydroxyzine, cetirizine, levocetirizine, or any component of the formulation. Patients with a prolonged QT interval, or a family history of prolonged QT interval, slow or irregular heartbeat, heart failure, heart attack, or other types of heart disease. Pregnancy and breastfeeding. Use with caution in older adults due to increased risk of side effects.

Drug Interactions

Hydroxyzine can interact with other medications, particularly those that also cause drowsiness or affect the central nervous system, such as other antihistamines, sedatives, tranquilizers, and alcohol. It should not be taken with drugs that prolong the QT interval due to the risk of irregular heartbeat. Always inform your doctor and pharmacist about all prescription, nonprescription, vitamins, and nutritional supplements you are taking.

Atarax FAQs

Hydroxyzine is used to treat anxiety and tension, to help with sleep before surgery, and to relieve itching caused by allergic reactions like hives and eczema.

Hydroxyzine works by blocking histamine, a chemical in the body that causes allergic symptoms. It also reduces brain activity to help with anxiety and promote relaxation.

It is not recommended to consume alcohol while taking Hydroxyzine. Alcohol can increase side effects such as drowsiness, dizziness, and difficulty concentrating, and can dangerously enhance sedation.

Common side effects include dry mouth, confusion (especially in older adults), dizziness, and headache. More serious side effects can occur, so it's important to consult your doctor if you experience any unusual symptoms.

No, Hydroxyzine is a prescription-only medication and requires a doctor's prescription.

Hydroxyzine typically starts to show clinical effects within 15-30 minutes, with peak levels occurring around 2 hours after administration.

Written and Reviewed by Our Qualified Team

Dr. Sarah Mitchell

Authored by:

Dr. Sarah Mitchell

Lead Medical Reviewer

Find out more about our medical content authors and how we ensure the accuracy of our content.

Content last updated: 14 Apr 2026

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